SDM   Seed-based d Mapping
formerly "Signed Differential Mapping"
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SDM exploration of the results

Thresholding the results

Results from the corresponding model can be thresholded to a given uncorrected or corrected statistical significance level, obtaining peak coordinates, clusters breakdowns and NIfTI images. This will also open MRIcron brain viewer to display the results (if MRIcron is enabled; see Settings section for help on setting up MRIcron integration).

Please find citation information for the atlas by Catani, Thiebaut de Schotten et al below.

One-tailed vs two-tailed

As in most neuroimaging software, this dialog conducts a pair of one-tailed tests. To avoid doubling the false positive rate, please halve the statistical significance level (e.g., to 0.025).

To threshold a map

Press the button [Threshold]


Select [Threshold] in the Statistics menu, to open the following dialog:

Threshold dialog

Command-line and batch usage

threshold p_map_path,z_map_path,value,minimum number of voxels


threshold analysis_MyMean/corrp_tfce,analysis_MyMean/MyMean_z,0.05,10

Note: p-map and z-map paths should NOT include the extension .nii.gz


(effect-sizes and variances): Radua J, Mataix-Cols D, Phillips ML, El-Hage W, Kronhaus DM, Cardoner N and Surguladze S. A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps. Eur Psychiatry 2012; 27:605–611. link .

(white matter atlas 1): Thiebaut de Schotten M, Dell'Acqua F, Forkel SJ, Simmons A, Vergani F, Murphy DG and Catani M. A lateralized brain network for visuospatial attention. Nat Neurosci 2011; 14:1245-1246. link .

(white matter atlas 2): Thiebaut de Schotten M, Ffytche DH, Bizzi A, Dell'Acqua F, Allin M, Walshe M, Murray R, Williams SC, Murphy DG and Catani M. Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractography. Neuroimage 2011; 54:49-59. link .

(white matter atlas 3): Rojkova K, Volle E, Urbanski M, Humbert F, Dell'Acqua F and Thiebaut de Schotten M. Atlasing the frontal lobe connections and their variability due to age and education: a spherical deconvolution tractography study. Brain Struct Funct 2015; in Press. link .